A New Frontier in Eczema Care

Atopic dermatitis is multifactorial: a weakened skin barrier, inflammatory immune response, filaggrin deficiency, allergies, and environmental factors can all contribute to its pathogenesis. And the skin microbiome plays a bigger role in AD than previously thought. Approximately 80% of atopic dermatitis patients are overcolonized with Staph aureus.¹, ² This pathogenic bacteria isn’t just a cause of skin infections—it can drive atopic dermatitis flares.³ Repairing skin microbiome dysbiosis is critical to successfully managing atopic dermatitis.

A Novel Skincare Category

Biome therapeutics is a new category of care designed to restore skin microbiome health. At GladskinMD, we formulate products specifically designed for patients dealing with a variety of skin concerns. Our patented endolysin technology restores balance to the skin, empowering patients and clinicians to address skin microbiome health head-on. 

Patient-Centered Skincare

Most AD patients have tried all kinds of skincare products—usually via trial and error. They often end up using products that aren’t designed for their skin.

GladskinMD products are formulated with minimal ingredients, focusing on only what the skin needs. We leverage endolysin science and biome therapeutics to drive our production formulation and ingredient selection.

Skincare Industry

Mass Skincare Brands

  • Youthful skin
  • Minor skin imperfections
  • Dehydrated skin

Sensitive Skincare Brands

  • Reactive skin
  • Sun sensitive skin
  • Diffused redness
  • History of allergies
  • Health challenged skin

Cosmeceutical Brands

  • Aging concerns
  • Dry skin
  • Pigment concerns
  • Broken blood vessels
  • Sagging skin

Gladskin Biome Therapeutics

  • For patients with a variety of skin concerns.
  • Dry, eczema-prone skin
  • Redness-prone skin
  • Blemish-prone skin
  • Patient prone to shaving concerns
  • Health challenged skin
  • Usually recommended by healthcare provider

OTC Skincare Brands

  • Treatment for specific skin concerns
  • Often recommended by healthcare provider
  • FDA monograph

Prescription Brands

  • Approved treatment for specific skin concerns
  • Only available with prescription from healthcare providers

Generational Skincare for Every Stage of Life

AD patients of all ages require itch relief, barrier repair, and moisturization. But their skincare needs also change as they move through life. At GladskinMD, we believe that patients deserve skincare options that address generational concerns and fit the shape of their lives.

Infant & Toddler

School Age

Teen

Young Adult

Adult

Advanced Age

Infant & Toddler

  • Parent and caregiver approved
  • Safe for young, fragile skin
  • Easy for parents and caregivers to apply
  • Easy to use during bath and bedtime
  • Soothes diaper rash
  • Oat-free options

School Age

  • Parent and caregiver approved
  • Easy to self-apply
  • Easy to store in backpack or desk
  • Compatible with school, play, sports
  • Non-greasy feel for daytime use
  • Easy to use during bath and bedtime
  • Oat-free options
  • Fun and friendly

Teen

  • Parent and caregiver approved
  • Establishes healthy skincare and self-care routines
  • Works well with makeup
  • Integrates into shaving routine
  • Addresses potential acne
  • Compatible with school, sports, or extracurriculars
  • Easily stored in backpack, purse or locker
  • Non-greasy for daytime use
  • Can be applied on the go
  • Promotes confidence and self-esteem

Young Adult

  • Cosmetically elegant
  • School and work environment friendly
  • Skin aging prevention
  • Safe for use during pregnancy
  • Works well with makeup
  • Integrates into shaving routine
  • Easily stored in purse, computer bag, or briefcase
  • Non-greasy for daytime use

Adult

  • Cosmetically elegant
  • Skin aging solutions
  • Safe for use during pregnancy
  • Work environment friendly
  • Integrates into shaving routine
  • Easily stored in purse, computer bag, or briefcase
  • Non-greasy for daytime use

Advanced Age

  • Easy to apply
  • Multi-function ingredients
  • Moisturizing and hydrating
  • Addresses itch associated with aging
  • Caregiver approved

Inspired by Real People

Atopic dermatitis can be tough, but it doesn’t have to stop patients from thriving. We believe in creating skincare that helps patients minimize eczema’s impact so they can focus on what matters most: their lives.

  • Chronic Itch

    This primary symptom of AD is highly disruptive and impacts patients’ social, emotional, and professional lives.

  • Sleep Disturbance

    Adults and children with AD experience disrupted ⁴ sleep that can lead to poorer health outcomes.⁵ Their caregivers aren’t sleeping well either.⁶, ⁷

  • Skin Pain

    This seldom acknowledged AD symptom can be debilitating and difficult to manage.

  • School and Work Disruptions

    Itching attacks and uncomfortable skin can impact focus and make it hard to succeed at–or even attend–work or school.

  • Mental Health

    People with AD have higher rates of anxiety and depression ⁸ and are 44% more likely to exhibit suicidal ideation.⁹

  • Self Esteem & Relationships

    AD is a visible marker of difference that can impact patients’ confidence, sense of self and relationships with others.

Citations

1

¹ Kim JE, Kim HS. Microbiome of the Skin and Gut in Atopic Dermatitis (AD): Understanding the Pathophysiology and Finding Novel Management Strategies. J Clin Med. 2019 Apr 2;8(4):444. doi: 10.3390/jcm8040444. PMID: 30987008; PMCID: PMC6518061.

2

² Higaki, S., Morohashi, M., Yamagishi, T., & Hasegawa, Y. (1999). Comparative study of staphylococci from the skin of atopic dermatitis patients and from healthy subjects. International journal of dermatology, 38(4), 265–269. https://doi.org/10.1046/j.1365-4362.1999.00686.

3

³ Kong HH, Oh J, Deming C, Conlan S, Grice EA, Beatson MA, Nomicos E, Polley EC, Komarow HD; NISC Comparative Sequence Program; Murray PR, Turner ML, Segre JA. Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis. Genome Res. 2012 May;22(5):850-9. doi: 10.1101/gr.131029.111. Epub 2012 Feb 6. PMID: 22310478; PMCID: PMC3337431.

4

4: Ramirez FD, Chen S, Langan SM, et al. Association of Atopic Dermatitis With Sleep Quality in Children. JAMA Pediatr. 2019;173(5):e190025. doi:10.1001/jamapediatrics.2019.0025

5

5: Jonathan I. Silverberg, Nitin K. Garg, Amy S. Paller, Anna B. Fishbein, Phyllis C. Zee,

Sleep Disturbances in Adults with Eczema Are Associated with Impaired Overall Health: A US Population-Based Study, Journal of Investigative Dermatology, Volume 135, Issue 1, 2015, Pages 56-66, ISSN 0022-202X, https://doi.org/10.1038/jid.2014.325. (https://www.sciencedirect.com/science/article/pii/S0022202X15370469).

6

6: McCleary KK. More Than Skin Deep: Understanding the Lived Experience of Eczema. Paper presented at: Eczema Patient-Focused Drug Development Meeting; March, 2020, 2019.

7

7: Angelhoff C, Askenteg H, Wikner U, Edell-Gustafsson U. “To Cope with Everyday Life, I Need to Sleep” – A Phenomenographic Study Exploring Sleep Loss in Parents of Children with Atopic Dermatitis. J Pediatr Nurs. 2018;43:e59-e65.

8

8: Schonmann Y, Mansfield KE, Hayes JF, Abuabara K, Roberts A, Smeeth L, Langan SM. Atopic Eczema in Adulthood and Risk of Depression and Anxiety: A Population-Based Cohort Study. J Allergy Clin Immunol Pract. 2020 Jan;8(1):248-257.e16. doi: 10.1016/j.jaip.2019.08.030. Epub 2019 Aug 31. PMID: 31479767; PMCID: PMC6947493.

9

9: Sandhu, J. K., Wu, K. K., Bui, T. L., & Armstrong, A. W. (2019). Association Between Atopic Dermatitis and Suicidality: A Systematic Review and Meta-analysis. JAMA dermatology, 155(2), 178–187. https://doi.org/10.1001/jamadermatol.2018.4566